A trip down the M5 follows a midweek home match for the Reds as they travel to Exeter tomorrow.
John Coleman’s team are out to make it six points from the week following the victory over Hartlepool and complete the double over the Grecians.
Exeter City are in their fourth successive season in League Two following relegation from the third tier in 2012.
They’d been members of the Football League from 1920 to 2003 before being relegated to the Conference but secured back to back promotions in 2009 and 2010.
The Grecians were play-off contenders last season with their challenge just faltering in the final few weeks. They ultimately finished in tenth spot.
Tisdale is in his 10th campaign as Exeter City boss, making him the longest-serving manager in the Football League.
He succeeded Alex Inglethorpe as manager in 2006 after leaving Team Bath. He took the Grecians from the Conference to League One but, due to budgetary constraints, has had to be shrewd in the transfer market.
Since he took over at City, the club has had one of the highest percentages of its Academy youngsters playing in its first team in the Football League, with the likes of Matt Grimes, Tom Nichols, Jordan Moore-Taylor and Jordan Tillson all regularly representing the first team in recent years
Striker Tom Nichols is an Academy graduate who made his debut for City at the age of just 17, just weeks after signing a professional deal at the end of the 2010/11 season.
He joined the Grecians in the under-11 age group and went on to score his first senior goal against Chesterfield the day before his 18th birthday, contributing to a 2-1 win at the beginning of the 2011/12 season.
He’s the top scorer for City this season so far, knocking in eleven goals in total.
The Reds are looking to make it three wins in a row after victories over Mansfield and Hartlepool.
Coleman’s men have suffered just one away league defeat since mid-October, with that coming at high flying Northampton last month.
They sit sixth in the table ahead of kick off, three points better off than eighth placed Wimbledon and four behind Bristol Rovers who are fourth.
Exeter’s recent results have been a mixed bag, with a terrific league win at Leyton Orient and a 2-2 home draw against Liverpool in the FA Cup standing out.
They lost the replay at Anfield in midweek and will be keen for a return to winning ways at the first attempt.
Tisdale’s team are currently 14th, six points from the play-off spots.
Dean Winnard has undergone successful surgery on a chest muscle and will be out for the foreseeable future as he recovers.
Josh Windass remains doubtful with a groin problem.
Defender Tom Davies dropped out of the eleven in midweek due to illness but did play in the Lancashire Cup on Wednesday and should be available.
The club have played at St James Park since forming in 1904. The current capacity of the ground is 8541, and the clubs record attendance is 20,984 which was set in the FA Cup against Sunderland in 1931.